High prevalence of clarithromycin resistance and cagA, vacA, iceA2, and babA2 genotypes of Helicobacter pylori in Brazilian children.

نویسندگان

  • Gabriella T Garcia
  • Katia R S Aranda
  • Manoel E P Gonçalves
  • Silvia R Cardoso
  • Kiyoshi Iriya
  • Neusa P Silva
  • Isabel C A Scaletsky
چکیده

We isolated 45 Helicobacter pylori strains from 217 child patients. Resistance to clarithromycin, metronidazole, amoxicillin, and tetracycline was detected in 27%, 13%, 4%, and 0% of strains, respectively. The A2143G mutation was the most prevalent (67%) among clarithromycin-resistant strains. In addition, strain genotyping revealed a significant association between gastritis severity and the simultaneous presence of cagA, vacA s1m1, iceA2, and babA2 genes.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 48 11  شماره 

صفحات  -

تاریخ انتشار 2010